Journal: BMC Gastroenterology
Article Title: Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity
doi: 10.1186/1471-230X-11-125
Figure Lengend Snippet: Effect of treatment with RLS or saline on PCNA in mice with ALI . PCNA staining was assessed 24 h, 48 h after induction of ALI (or sham procedure). Figure 7A, B and C, the method and treatment were the same as described in Figure 1A and 1B (n = 5 for each group). Figure 7D and 7E: three separate groups of mice were used. ALI was induced the same as Figure 1 A and B. 2 hrs after APAP challenge, the animals were given the same treatment every 12 hrs for a total of 48 hrs. PCNA was detected 48 hrs after APAP injection (n = 5 for each group). Results are means ± SEM. * indicates p < 0.05. Typical picture is shown.
Article Snippet: Sections from mouse liver following APAP challenge were prepared and processed for immunohistochemistry using PCNA staining kits from Invitrogen (Camarillo, CA, USA) according to the manufacturer's instructions.
Techniques: Staining, Injection